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2.5 Ranking Acids and Bases with CARDIO (Resonance) (Solution)

Lesson Summary

1. Which of the following molecules is most acidic? Why?

2. Which of the red-colored hydrogen atoms in the molecules below is most acidic? Why?

3. Which of the labeled hydrogen atoms in the following structure is the most acidic?

4. Which of the labeled hydrogen atoms in the following structure is the most acidic?

5. Which of the labeled hydrogen atoms in the following structure is the most acidic?

6. The pKA of acetone is about 20. The pKA of propanone is about 50. Why?

7. Which of the red-colored alpha-hydrogen atoms is the LEAST acidic?

8. Sort the compounds below in order of increasing acidity of their alpha-hydrogen atoms (colored red), from LEAST to MOST acidic: